僅用于工業(yè)應(yīng)用或科學(xué)研究,不可用于人類或動物的臨床診斷或治療,非藥用.Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity.Docetaxel (RP-56976) 是一種微管解聚 (microtubule depolymerization) 抑制劑,其 IC50 值為 0.2 μM。Docetaxel 是紫杉醇的半合成類似物,能減弱 bcl-2 和 bcl-xL 基因表達的影響。Docetaxel 阻滯 G2/M 細(xì)胞周期,導(dǎo)致細(xì)胞凋亡 (apoptosis)